Haematology: Treating patients with blood disorders in ICU

This one-day event brings together a diverse group of experts to discuss crucial topics at the intersection of haematology and critical care. Our distinguished faculty will cover a wide range of subjects, including the management of sickle cell anaemia, red cell and platelet transfusions in an ICU setting, and the challenges of treating cytokine release syndrome and ICANs in critically ill patients.

We will also explore the potential for VV-ECMO in patients with malignancy and delve into the latest research on immunothrombosis and models of haemostasis and thrombosis. Attendees will gain valuable insights into monitoring anticoagulation in critical care, diagnosing and managing heparin-induced thrombocytopenia, and the treatment of TTP in the critical care setting. This comprehensive program is designed to enhance the knowledge and skills of consultants, junior doctors, and allied health care professionals working in intensive care.

Learning outcomes

Management of sickle cell anaemia in ITU:

Recognise the unique challenges and complications of managing sickle cell anaemia patients in the intensive care setting.
Understand the importance of early intervention and multidisciplinary care in improving patient outcomes.
Identify key strategies for managing acute chest syndrome, vaso-occlusive crises, and other sickle cell-related complications in the ITU.

Management of red cell transfusions on ICU:

Understand the indications and risks associated with red cell transfusions in critically ill patients.
Learn about evidence-based transfusion thresholds and strategies for minimizing transfusion-related complications.
Discuss the role of alternative therapies, such as erythropoiesis-stimulating agents, in reducing the need for red cell transfusions on the ICU.

Management of platelet transfusions in ICU:

Recognise the indications and contraindications for platelet transfusions in critically ill patients.
Understand the importance of platelet count monitoring and the use of platelet function tests in guiding transfusion decisions.
Discuss strategies for preventing and managing platelet refractoriness and other transfusion-related complications.

Management of cytokine release syndrome and ICANs in patients admitted to critical care:

Understand the pathophysiology and clinical presentation of cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome (ICANs) in critically ill patients.
Learn about the grading systems and diagnostic criteria for these conditions.
Discuss the latest evidence-based management strategies, including the use of tocilizumab and corticosteroids, for treating cytokine release syndrome and ICANs in the critical care setting.

Immunothrombosis and models of haemostasis and thrombosis:

Understand the concept of immunothrombosis and its role in the pathogenesis of thrombotic disorders in critically ill patients.
Learn about the latest research on the interplay between the immune system and the coagulation cascade.
Discuss the implications of immunothrombosis for the development of novel diagnostic and therapeutic strategies in the management of thrombosis on the ICU.

The diagnosis and management of heparin-induced thrombocytopenia on ICU:

Recognise the clinical features and risk factors for heparin-induced thrombocytopenia (HIT) in critically ill patients.
Understand the diagnostic approach to HIT, including the use of immunoassays and functional assays.
Learn about the management strategies for HIT on the ICU, including the use of alternative anticoagulants and the role of plasma exchange in severe cases.

The management of TTP in critical care:

Understand the pathophysiology and clinical presentation of thrombotic thrombocytopenic purpura (TTP) in critically ill patients.
Learn about the diagnostic criteria and the role of ADAMTS13 testing in the diagnosis of TTP.
Discuss the management strategies for TTP in the critical care setting, including the use of plasma exchange, immunosuppressive therapy, and novel therapies such as caplacizumab.

Programme

Welcome and introduction - Andrew Retter, Chair
10am - Management of sickle cell anaemia on ICU - Rachel Kesse-Adu
10:40am - Management of red cell transfusions on ICU - Simon Stanworth
11:15am - Management of platelet transfusions on ICU - Duncan Wyncoll
11:45am - Break
12pm - Management of tumour lysis syndrome -
12:20pm - Management of cytokine release syndrome and ICANs in patients admitted to critical care - Claire Roddy
12:50pm - Candidates for VV-ECMO with malignancy -
1:15pm - Lunch
2:00pm - Immunothrombosis and models of haemostasis and thrombosis - Andrew Retter
2:30pm - Monitoring anticoagulation in critical care - Teddy Hla and Fraser Hanks
2:50pm - Break
3pm - The diagnosis and management of heparin induced thrombocytopenia on ICU - Andrew Doyle
3:25pm - The management of TTP in critical care - Marie Scully
4pm - Close

Group bookings

Group bookings can be made for multiple delegates and paid by credit card via the event booking page.

We are also able to invoice for group bookings of 10 or more delegates, or where the total value is over £1,000. Group bookings can only be made up to 6 weeks in advance of an event and must be paid in full prior to the event date to avoid tickets being cancelled.

To book a group via invoice, please download the form below, complete and return to events@ics.ac.uk.