3.30pm – 4.45pm BST, 1 July 2025 ‐ 1 hour 15 mins
Stream 1
Outline of proposed content:
Sepsis and infections affect a large number of critically ill patients and present multiple challenges. The aim of this session is to bring you up to speed with the latest evidence-base and controversies to help manage infections and antibiotics. It will focus on the ADAPT-Sepsis and A-STOP trials reporting on how biomarkers help us with decision making on antibiotics and antifungal usage, the implications of the BLING III trial and implementation of the results, what implementation science can tell us about the SuDDICU trial and use of selective decontamination of the gut.
Learning objectives
1) How can we use biomarkers to manage antimicrobials in the ICU
2) Understand the outcomes from BLING III trial and how we can implement it’s findings
3) What is SDD and what are the implementation considerations
Co-Chairs: Jan de Waele and Stephen Brett
Vice Dean for Health and Care Partnerships, University of Manchester
Consultant Pharmacist, King’s College Hospital NHS Foundation Trust & Chair of ICS Learning Division
Professor of Critical Care and Intensive Care Consultant, Imperial College London
Professor of Medical Microbiology, Queens University Belfast & Belfast HSC Trust
President, ESICM
President of ESICM, Full Professor at Universiteit Gent, Intensivist at Ghent University Hospital, Senior Clinical Investigator at the Research Foundation Flanders.
Vice Dean for Health and Care Partnerships, University of Manchester
Paul studied undergraduate physics and medicine. Graduating from The Manchester Medical School, he went on to study clinical academic surgery, emergency medicine and critical care at the Universities of Glasgow and Manchester in the UK, and at the Catholic University of Leuven, Belgium.
:
https://www.linkedin.com/in/paul-dark-33002722?lip
:
@https://x.com/darknatter
Professor of Critical Care Nursing, UK
Professor Louise Rose, RN, PhD is a Professor of Critical Care Nursing at King’s College London, UK and an honorary Professor in Critical Care and the Lane Fox Respiratory Unit at St Thomas’ Hospital in London. Prior to joining King’s she was an Associate Professor at the University of Toronto. Her research program focuses on improving outcomes and the healthcare experience of mechanically ventilated patients across the care continuum from the emergency department, intensive care unit, specialised weaning centre and in the home. She also has extensive clinical experience in critical care in four countries. Since commencing her research career she has been awarded 90 peer reviewed research grants and has over 180 peer reviewed publications.Consultant Pharmacist, King’s College Hospital NHS Foundation Trust & Chair of ICS Learning Division
Reena is a Consultant Pharmacist in Critical Care at King’s College Hospital NHS Foundation Trust, London and Chair of the Intensive Care Society’s Learning Division.
Her specialist areas of interest are anti-microbial stewardship, medicines use in extra-corporeal circuits and health inequalities.
She has worked in Critical Care for over 15 years, and has co-authored and provided specialist input nationally into areas such as pharmacy critical care workforce, clinical guidelines, and advanced critical care training. Reena is an Associate Editor for the Journal of the Intensive Care Society and an Honorary Senior Lecturer at King’s College London. Within her organisation, she is a Principal Investigator on a number of CRN Portfolio studies
Reena is also the Pharmacy Lead for the South East London ICS - Critical Care/ODN and a member of the United Kingdom Adult Critical Care Pharmacy Leadership Forum. She has recently completed an MSc in Health Economics, Policy & Management at the London School of Economics and Political Science.
Professor of Critical Care and Intensive Care Consultant, Imperial College London
Professor Stephen Brett is Professor of Critical Care at Imperial College London and a consultant in intensive care medicine at Imperial College Healthcare NHS Trust, looking after patients at Hammersmith Hospital. He is also a previous president of the Intensive Care Society; he chaired the original NICE guideline development group for "Rehabilitation after Critical Illness", and was a member of SPI-M-O during the COVID pandemic. His research interests are wide, ranging from clinical trials and outcomes research through organisational and decision-making to the use of artificial intelligence and machine learning for event prediction.
Professor of Medical Microbiology, Queens University Belfast & Belfast HSC Trust
Ronan McMullan is a Consultant Microbiologist at Belfast Trust and Professor of Medical Microbiology at Queen’s University Belfast. His MD was focused on the development and assessment of the diagnostic accuracy of a Candida PCR test in ICU patients and he continues to pursue research on diagnostic tests for infection.
Ronan has been a member of NIHR prioritisation and funding committees (with the HTA and EME programmes) for hospital-based research. He is also Clinical Director of training & Assessment with the Royal College of Pathologists and has previously been an Education Associate with the GMC Curriculum Advisory Group.
His main research interests are in antimicrobial stewardship and diagnostic accuracy studies. Ronan’s current research is focused on use of rapid tests as an antifungal stewardship tool in critical care. He has a leadership role in several national trials, most of which are funded by the NIHR HTA programme.