1.30pm – 2.45pm BST, 1 July 2025 ‐ 1 hour 15 mins
Stream 2
A case led evidence review session
We will talk through a case, and at each juncture cover the recent / pertinent published data that supports our decision making in the diagnosis and management of a patient who develops AKI
Patient: e.g. Obese, having major surgery, history of type II DM, HTN and previous cardiac stent
Learning objectives
1) Learn how to stratify the of AKI in patients going for major surgery
2) Review recent developments in the diagnosis and treatment (non CRRT) of AKI
3) To be able to consider the choices and variations in CRRT to best suit the needs of the patient
4) Understand the value, or not, in following up patients who have had severe AKI
Clinical Reader in Critical Care Nephrology, Queen Mary University of London and Consultant Intensivist & Nephrologist, Barts Health NHS Trust
Clinical Reader in Critical Care Nephrology, Queen Mary University of London and Consultant Intensivist & Nephrologist, Barts Health NHS Trust
Dr Prowle is Clinical reader in Critical Care Nephrology in the Critical Care and Perioperative Medicine Research Group at William Harvey Research Institute, Queen Mary University of London and is an Honorary Consultant Physician in Intensive Care Medicine and Renal Medicine at the Royal London Hospital, Barts Health NHS Trust.
Dr Prowle graduated with distinction in medicine from the University of Cambridge in 1999 and undertook Doctoral Research under the supervision of Prof Rinaldo Bellomo (the most published and highly cited researcher in the history of Australian Medicine) in Melbourne, Australia leading to the award of his MD research doctorate in 2012.
His research interests include the pathogenesis, diagnosis and outcomes of Acute Kidney Injury, Renal replacement Therapy in the ICU the Epidemiology of Critical Illness and its recovery and the impact of multi-morbidity of high risk surgical and ICU outcomes. Since 2009 he has co-authored over 160 peer-reviewed publications and 30 book chapters with an H-index of 51 (GS).
He is an active senior contributor to national and international collaborations in critical care nephrology including the Acute Disease Quality Initiative (ADQI), Kidney Disease Improving Global Outcomes AKI Group and the UK Kidney research Consortium Clinical Studies Group in AKI (as co-chair).
Consultant Intensivist and Nephrologist, University of Galway
Dr. Bairbre McNicholas is a dual-trained Consultant in Intensive Care Medicine and Nephrology at Galway University Hospitals (GUH) and a Senior Clinical Lecturer at the University of Galway. She completed her PhD on early inflammation in obesity and type 2 diabetes as part of the National Specialist registrar academic fellowship programme and following this, completed a basic science research fellowship at the University of Washington, Seattle USA. She completed training in Intensive Care Medicine in Ireland in 2017. Dr. McNicholas has led and collaborated on numerous clinical trials such as REMAP-CAP and REACT-SHOCK, Awake-prone meta trial group and studies on the immunology of sepsis and epidemiology of acute kidney injury. Dr. McNicholas is the CRRT lead for Ireland’s Acute Critical Care Programme, the AKI Pathway Lead for ESICM. She has published over 60 peer-reviewed articles and two book chapters, and is co-chair of the RCPI Climate Advisory Group.
Royal London Hospital, Barts Health NHS Trust
After training in various London University Teaching Hospitals, Chris was appointed a consultant in Critical Care Medicine and Nephrology at The Royal London Hospital in 2012 and Honorary Clinical Senior Lecturer at Barts and The London school of Medicine soon after. His main research interests include improving the recognition and outcomes of Acute Kidney Injury (AKI) and especially its long-term effect on renal function, the effect of AKI on hepatic drug metabolism and the peri-operative care of renal transplant patients. More recently Chris has focused on the evolving role of CRRT in acutely ill patients particularly the use of regional citrate anticoagulation, dynamic dosing and the importance of access in successful therapy, as well as the role of intermittent dialysis in supporting critically ill patients.
ICS Director of Research, Consultant Intensivist and Nephrology, UK
Marlies is a Consultant in Critical Care & Nephrology at Guy’s & St. Thomas’ Foundation Trust, London and Honorary Senior Lecturer at King’s College London.
Following medical school in Goettingen (Germany), she completed her postgraduate training in the United Kingdom and Canada. She is one of the Directors of Research at the Intensive Care Society, and actively involved in the Renal Association. She is Deputy Chair of the AKI working group of the European Society of Intensive Care Medicine.
Her clinical and research interests include acute kidney injury in the critically ill, including biomarkers and long-term complications, and all aspects related to acute renal replacement therapy.